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The American Biology Teacher

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Trying Out Genes for Size
Experiential Learning in the High School Classroom
Joshua D. Blazek, Gary L. Cooper, Mariah V. Judd, Randall J. Roper, Kathleen A. Marrs
The American Biology Teacher, Vol. 75 No. 9, November/December 2013; (pp. 657-662) DOI: 10.1525/abt.2013.75.9.6
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
Gary L. Cooper (glcooper@pike.k12.in.us ) is a Biology Teacher at Indianapolis Pike High School.
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
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Abstract

The National Science Foundation’s GK–12 program provides a unique opportunity for STEM collaboration between the K–12 classroom and university research. This partnership benefits students through experiential learning, exposure to research, exceptional mentorship, and preparation for postsecondary education. Additionally, researchers gain valuable skills by explaining difficult scientific concepts to high school students and broadening their exposure to secondary education. We present graduate-research-based activities focused on understanding the genetic causes of Down syndrome. Modification of these activities could accommodate educational levels from middle school to entry-level college biology. This lesson involves several biological and data-collecting techniques. These experiential activities help students understand genetics and Down syndrome, and introduce basic scientific methodology and techniques useful for postsecondary education.

Key Words:
  • Down syndrome (DS)
  • mouse model
  • trisomy
  • phenotype
  • genotyping
  • statistical analysis
  • © 2013 by National Association of Biology Teachers. All rights reserved. Request permission to photocopy or reproduce article content at the University of California Press’s Rights and Permissions Web site at http://www.ucpressjournals.com/reprintinfo.asp.
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Vol. 75 No. 9, November/December 2013

The American Biology Teacher: 75 (9)
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Trying Out Genes for Size
Experiential Learning in the High School Classroom
Joshua D. Blazek, Gary L. Cooper, Mariah V. Judd, Randall J. Roper, Kathleen A. Marrs
The American Biology Teacher, Vol. 75 No. 9, November/December 2013; (pp. 657-662) DOI: 10.1525/abt.2013.75.9.6
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
Gary L. Cooper (glcooper@pike.k12.in.us ) is a Biology Teacher at Indianapolis Pike High School.
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.

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Trying Out Genes for Size
Experiential Learning in the High School Classroom
Joshua D. Blazek, Gary L. Cooper, Mariah V. Judd, Randall J. Roper, Kathleen A. Marrs
The American Biology Teacher, Vol. 75 No. 9, November/December 2013; (pp. 657-662) DOI: 10.1525/abt.2013.75.9.6
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
Gary L. Cooper (glcooper@pike.k12.in.us ) is a Biology Teacher at Indianapolis Pike High School.
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
Joshua D. Blazek (jblazek@iupui.edu) is a Ph.D. student and NSF GK-12 Fellow in Biology, Mariah V. Judd (mjudd@iupui.edu) is a Postdoctoral Fellow in Biology, Randall J. Roper (rjroper@iupui.edu) is an Assistant Professor of Biology, and Kathleen A. Marrs (kmarrs@iupui.edu) is Associate Professor of Biology, all at University-Purdue University Indianapolis, 723 W. Michigan St., SL 306, Indianapolis, IN 46202.
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  • Top
  • Article
    • Abstract
    • Down Syndrome, a Familiar Disorder to Teach Genetics
    • Activity 1: Discovering Genetic Disorders & How They Are Studied
    • Activity 2: Genotyping Ts65Dn Mice to Determine Patterns of Inheritance
    • Activity 3: Assessing the Nuclear Localization of Nfat in the Trisomic Mandibular Precursor
    • Discussion
    • Acknowledgments
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

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