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The American Biology Teacher

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RNA Interference
An Instant Update on the Mechanism, Functions, & Therapeutic Applications
Yin Kiong Hoh
The American Biology Teacher, Vol. 76 No. 6, August 2014; (pp. 373-377) DOI: 10.1525/abt.2014.76.6.4
YIN KIONG HOH is a Senior Lecturer in Natural Sciences and Science Education at the National Institute of Education, Nanyang Technological University, 1 Nanyang Walk, Singapore 637616; e-mail: yinkiong.hoh@nie.edu.sg.
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Abstract

This article reviews the discovery of RNA interference, its mechanism of action and its functions, and the principles, challenges, and strategies for RNA therapeutics.

Key Words:
  • RNA interference
  • small interfering RNA
  • microRNA
  • RNA-interference-based therapies
  • © 2014 by National Association of Biology Teachers. All rights reserved. Request permission to photocopy or reproduce article content at the University of California Press’s Rights and Permissions Web site at http://www.ucpressjournals.com/reprintinfo.asp.
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Vol. 76 No. 6, August 2014

The American Biology Teacher: 76 (6)
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RNA Interference
An Instant Update on the Mechanism, Functions, & Therapeutic Applications
Yin Kiong Hoh
The American Biology Teacher, Vol. 76 No. 6, August 2014; (pp. 373-377) DOI: 10.1525/abt.2014.76.6.4
YIN KIONG HOH is a Senior Lecturer in Natural Sciences and Science Education at the National Institute of Education, Nanyang Technological University, 1 Nanyang Walk, Singapore 637616; e-mail: yinkiong.hoh@nie.edu.sg.

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RNA Interference
An Instant Update on the Mechanism, Functions, & Therapeutic Applications
Yin Kiong Hoh
The American Biology Teacher, Vol. 76 No. 6, August 2014; (pp. 373-377) DOI: 10.1525/abt.2014.76.6.4
YIN KIONG HOH is a Senior Lecturer in Natural Sciences and Science Education at the National Institute of Education, Nanyang Technological University, 1 Nanyang Walk, Singapore 637616; e-mail: yinkiong.hoh@nie.edu.sg.
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  • Top
  • Article
    • Abstract
    • Introduction to RNA Interference
    • Discovery of RNA Interference
    • Mechanism of RNA Interference
    • Functions of RNA Interference
    • Other Cellular Pathways Similar to RNA Interference
    • Applications of RNA Interference in Medicine & Biomedical Research
    • Challenges of RNA Therapeutics
    • Strategies for RNA Therapeutics
    • Conclusion
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

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